After their wedding, and Honeymoon which is filmed in Lough Inagh and Ballynahinch Castle Hotel in Connemara. Jennifer Aniston (Jennifer Grogan) and Owen Wilson (John Grogan), both newspaper writers, move to Florida. An attempt to stall Jennifer’s “biological clock”, John gives her a puppy. While the puppy Marley grows up, he loses none of his puppy energy or rambunctiousness. Marley’s antics give John rich material for his newspaper column. As John and Jen mature and have children of their own, Marley continues to test everyone’s patience by acting like the world’s worst dog truly bringing out the best in them.